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產(chǎn)品目錄
  • 細(xì)胞培養(yǎng)進(jìn)口血清
    進(jìn)口胎牛血清
    進(jìn)口新生牛血清
    進(jìn)口豬血清
    馬血清
  • 支原體檢測盒及標(biāo)準(zhǔn)品
    常規(guī)PCR檢測試劑盒
    熒光定量PCR檢測(qPCR法)
    支原體DNA提取
    靈敏度標(biāo)準(zhǔn)品(方法驗證用)
    特異性標(biāo)準(zhǔn)品(方法驗證用)
    PCR定量標(biāo)準(zhǔn)品(可用于方法驗證)
  • 支原體祛除試劑
    細(xì)胞中支原體祛除
    環(huán)境支原體祛除
    水槽支原體祛除
  • 干細(xì)胞培養(yǎng)基
  • DNA/RNA污染祛除
    DNA/RNA污染祛除試劑
    DNA污染監(jiān)測
  • RNA病毒研究試劑
    RNA病毒檢測試劑盒
    病毒RNA提取
  • PCR儀器及配套產(chǎn)品
    DNA污染監(jiān)測祛除
    PCR/qPCR儀性能檢查
    PCR試劑
    PCR試劑盒
    PCR預(yù)混液(凍干粉)
    熱啟動聚合酶MB Taq DNA
  • 微生物PCR檢測
    食品檢測類產(chǎn)品
    食品微生物檢測
    細(xì)菌PCR檢測

利用微生物培養(yǎng)基的景觀來預(yù)測新的有機(jī)體媒體配對

2016-09-27 14:39

KOMODO reveals global patterns of media and compound usage

Typical patterns of media usage and composition in KOMODO can reveal fundamental trends in microbial nutrition, as well as gaps and investigator biases. To gain an overview of these relationships, we built histograms of component, media and organism distributions across the database (Fig. 2a–d). We observed that component usage across media, and media usage across organisms both follow power-laws, which suggests a ‘rich gets richer’ structure to the assignment of phenotypes and component usages (Fig. 2a,b). This structure might reflect converging nutrient requirements among organisms, the preferential way in which ‘successful’ media are selected for organisms by human investigators, or both.

Figure 2: Large-scale properties of known media.

(a) Distributions of components in media. This includes both defined and complex/undefined components, where undefined components are grouped into their complex categories and each category present in a medium is counted as one component.

(b) Distributions of media by the number of organisms that grow on them.

(c) Distributions of the number of media that organisms grow on.

(d) Distribution of media by the number of components within them.

(e) Distribution of pH values of known media. Red squares in a and b denote the bins used for the power law fit.

(f) The 40 most frequently used media components across genera. Ions listed here were typically added to media as salts, which we assume completely dissociate in solution (for example, MgCl2 becomes Mg2+ and Cl?). Components are broken into four groups: biologically common ions/compounds, trace metals/metalloids, vitamins/coenzymes and other. Within each group, components are listed in order of their frequency of usage across genera, from most to least. Left of the bar graphs is a list of average concentrations of each component in media across KOMODO, listed in units of log10(molar concentration). A component is ‘differential’ in a genus if it appears in media for some strains in that genus but not others.

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